Publications
SELECTED PUBLICATIONS
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González-González A, Soria-Utrilla V, Fontalba-Romero MI, Núñez-Sánchez MÁ, Adarve-Castro A, Queipo-Ortuño MI, Ramos-Molina B (CA), Martínez-Montoro JI, Fernández-García JC. 2026. The Role of Butyrate in People with Metabolic Dysfunction-Associated Steatotic Liver Disease and Related Metabolic Comorbidities: A Systematic Review. Curr Obes Rep. 2026 Mar 4;15(1):17. doi: 10.1007/s13679-026-00694-8 | PMID: 41779349
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Martínez-Sánchez MA, Ros-Madrid I, Fernández-Ruiz VE, Cano-Mármol RP, Hernández-Morante JJ, Núñez-Sánchez MÁ, Balaguer-Román A, Frutos-Bernal MD, Ruiz-Alcaraz AJ, Queipo-Ortuño MI, Ferrer-Gómez M, Ramos-Molina B (CA). 2026. Mid-Term Changes in Quality of Life and Nutritional Habits Following Gastric Bypass: A 24-Month Follow-Up Study. Nutrients. 2026 Jan 16;18(2):288. doi: 10.3390/nu180202888 | PMID: 41599901
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Han H, Park J, Zhang R, Subramaniyam N, Das S, Ge X, Babu Komakula SS, Wang C, Desert R, Chen W, Song Z, Athavale D, Anwar A, Lantvit D, Guzman G, Frutos MD, Ramos-Molina B, Nieto N. 2026. Intestinal Epithelial Cell-derived Osteopontin Protects Against Metabolic Dysfunction-associated Steatohepatitis by Modulating Bile Acid Composition and the Gut Microbiome. Cell Mol Gastroenterol Hepatol. 2026; 20(3):101678. doi: 10.1016/j.jcmgh.2025.101678 | PMID: 41241180
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Cai Z, Najib S, Núñez-Sánchez MA, Martínez-Sánchez MA, García-Melgares C, Viguerie N, Rossell J, Julve J, Croyal M, Oliveira AR, Martínez CM, Dumas SJ, Genoux A, Frutos MD, Ramos-Molina B (CLA), Martinez LO. 2025. ApoJ and apoL1 as novel determinants of MASH: a cross-sectional study. Lipids Health Dis. doi: 10.1186/s12944-025-02733-0 | PMID: 41088161
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Suárez-Cortés M, Juan-Pérez A, Molina-Rodríguez A, Araújo de Castro J, Castaño-Molina MÁ, Fernández-Ruiz VE, Jiménez-Méndez A, Martínez Pérez-Munar P, Rico-Chazarra S, Ramos-Molina B, Sánchez-Solís M, Blanco-Carnero JE, Ruiz-Alcaraz AJ, Núñez-Sánchez MÁ. 2025. Dynamics of the Epigenome, Microbiome, and Metabolome in Relation to Early Adiposity in the Maternal-Infant Axis: Protocol for a Prospective, Observational Pilot Study in the Spanish NEMO Cohort. J Clin Med. 2025 Sep 23;14(19):6694. doi: 10.3390/jcm14196694 | PMID: 41095773
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Garcia CJ, García-Villalba R, Frutos-Lisón MD, Beltrán D, Martínez-Sánchez MA, Núñez-Sánchez MÁ, Ramos-Molina B, Tomás-Barberán FA. 2025. Novel Insights into the Human Gut Microbially Conjugated Bile Acids: The New Diversity of the Amino Acid-Conjugated Derivatives. J Agric Food Chem. doi: 10.1021/acs.jafc.5c03548 | PMID: 40705851
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Pérez-Díaz AJ, Ros-Madrid I, Martínez-Sánchez MA, Rico-Chazarra S, Oliva-Bolarín A, Balaguer-Román A, Fernández-Ruiz VE, Martínez CM, Yuste JE, Ferrer-Gómez M, Llamoza-Torres CJ, Frutos MD, Núñez-Sánchez MÁ (CA), Ramos-Molina B (CA). 2025. Alterations in hepatic amino acid metabolism related to MASLD in individuals with obesity. J Physiol Biochem. doi: 10.1007/s13105-025-01086-7 | PMID: 40335876
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Kuchay MS, Choudhary NS, Ramos-Molina B. (CA). 2025. Pathophysiological underpinnings of metabolic dysfunction-associated steatotic liver disease. Am J Physiol Cell Physiol. doi: 10.1152/ajpcell.00951.2024 | PMID: 40244183
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Xu K, Corona-Avila I, Frutos MD, Núñez-Sánchez MÁ, Makhanasa D, Shah PV, Guzman G, Ramos-Molina B, Priyadarshini M, Khan MW. 2025. Hepatic HKDC1 deletion alleviates western diet-induced MASH in mice. Biochim Biophys Acta Mol Basis Dis. doi: 10.1016/j.bbadis.2025.167746 | PMID: 40020530
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Lamas-Paz A, Hionides-Gutiérrez A, et al., Ramos-Molina B, Aspichueta P, Puigserver P, Nevzorova YA, Cubero FJ. 2024. Loss of Cdkn1a protects against MASLD alone or with alcohol intake by preserving lipid homeostasis. JHEP Rep. doi: 10.1016/j.jhepr.2024.101230 | PMID: 39659733
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Núñez-Sánchez MÁ, Martínez-Sánchez MA, Ramos-Molina B (CA). 2024. Peroxisome proliferator-activated receptor gamma (PPAR-γ) activation through gut microbiota modulation as a novel therapeutic approach against anastomotic leak after colorectal cancer surgery. J Gastrointest Oncol. doi: 10.21037/jgo-24-314 | PMID: 39554579
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Núñez-Sánchez MÁ, Martínez-Sánchez MA (CFA), Sierra-Cruz M, Rico-Chazarra S, Oliva-Bolarín A, Balaguer-Román A, Yuste JE, Martínez CM, Mika A, Frutos MD, Llamoza-Torres CJ, Córdoba-Chacón J, Ramos-Molina B (CA). 2024. Increased hepatic putrescine levels as a new potential factor related to the progression of metabolic dysfunction-associated steatotic liver disease. J Pathol. doi: 10.1002/path.6330 | PMID: 39022853
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Ramos-Molina B, Rossell J, Pérez-Montes de Oca A, Pardina E, Genua I, Rojo-López MI, Julián MT, Alonso N, Julve J, Mauricio D. 2024. Therapeutic implications for sphingolipid metabolism in metabolic dysfunction-associated steatohepatitis. Front Endocrinol (Lausanne). doi: 10.3389/fendo.2024.1400961 | PMID: 38962680
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Martínez-Montoro JI, Martínez-Sánchez MA, Balaguer-Román A, Fernández-Ruiz VE, Hernández-Barceló JE, Ferrer-Gómez M, Frutos MD, Núñez-Sánchez MÁ, Fernández-García JC, Ramos-Molina B (CA). 2024. Triglyceride to HDL Cholesterol Ratio for the Identification of MASLD in Obesity: A Liver Biopsy-Based Case-Control Study. Nutrients. doi: 10.3390/nu16091310 | PMID: 38732557
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Pérez-Díaz AJ, Núñez-Sánchez MÁ (CA), Ramos-Molina B (CA). 2024. Revisiting liver metabolism through acetyl-CoA carboxylase inhibition. Trends Endocrinol Metab. doi: 10.1016/j.tem.2024.04.010 | PMID: 38664153
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Castellano-Castillo D, Ramos-Molina B (CFA), Frutos MD, Arranz-Salas I, Reyes-Engel A, Queipo-Ortuño MI, Cardona F. 2024. RNA expression changes driven by altered epigenetics status related to NASH etiology. Biomed Pharmacother. doi: 10.1016/j.biopha.2024.116508 | PMID: 38579398
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Núñez-Sánchez MA, Martínez-Sánchez MA (CFA), Martínez-Montoro JI, Balaguer-Román A, et al., Mika A, Ramos-Molina B (CA). 2024. Lipidomic analysis reveals alterations in hepatic FA profile associated with MASLD stage in patients with obesity. J Clin Endocrinol Metab. doi: 10.1210/clinem/dgae028 | PMID: 38217869
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Colosimo S, Martínez-Sánchez MA, Balaguer-Román A, Fernández-Ruiz VE, Núñez-Sánchez MA, et al., Marchesini G, Ramos-Molina B. 2023. A novel model for predicting diabetes remission after bariatric surgery based on the measurement of C-peptide and creatinine in serum: a pilot study. Nutr Metab Cardiovasc Dis. doi: 10.1016/j.numecd.2023.12.008 | PMID: 38220504
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Marsal-Beltran A, Rodríguez-Castellano A, et al., Ramos-Molina B, Aspichueta P, Joven J, Fernández-Real JM, Quer JC, Valverde ÁM, Pardo A, Vendrell J, Ceperuelo-Mallafré V, Fernández-Veledo S. 2023. Protective effects of the succinate/SUCNR1 axis on damaged hepatocytes in NAFLD. Metabolism. doi: 10.1016/j.metabol.2023.155630 | PMID: 37315889
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Zheng K, Hao F, Medrano-Garcia S, et al., Ramos Molina B, Herranz JM, Ávila MA, Nevzorova YA, Fernández-Malavé E, Cubero FJ. 2023. Neuroblastoma RAS viral oncogene homolog (N-RAS) deficiency aggravates liver injury and fibrosis. Cell Death Dis. doi: 10.1038/s41419-023-06029-y | PMID: 37563155
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Talamantes S, Lisjak M, Gilglioni EH, Llamoza-Torres CJ, Ramos-Molina B, Gurzov EN. 2023. Non-alcoholic fatty liver disease and diabetes mellitus as growing aetiologies of hepatocellular carcinoma. JHEP Reports. doi: 10.1016/j.jhepr.2023.100811 | PMID: 37575883
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Babiy B, Ramos-Molina B (CFA), Ocaña L, et al., Pastor O. 2023. Dihydrosphingolipids are associated with steatosis and increased fibrosis damage in non-alcoholic fatty liver disease. BBA Mol Cell Biol Lipids. doi: 10.1016/j.bbalip.2023.159318 | PMID: 37059386
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Martinez-Montoro JI, Núñez-Sánchez MA (CFA), Martinez-Sánchez MA, et al., Fernandez-Garcia JC, Mika A, Ramos-Molina B. 2023. Hepatic and serum branched-chain fatty acid profile in patients with nonalcoholic fatty liver disease: A case-control study. Obesity (Silver Spring). doi: 10.1002/oby.23711 | PMID: 36981620
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Martinez-Sánchez MA, Balaguer-Román A, Fernandez-Ruiz V, et al., Ruiz-Alcaraz AJ, Núñez-Sánchez MA (CA), Ramos-Molina B. 2023. Plasma short-chain fatty acid changes after bariatric surgery in patients with severe obesity. Surg Obes Relat Dis. doi: 10.1016/j.soard.2022.12.041 | PMID: 36842931
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Lee SM, Muratalla J, Karimi S, Diaz-Ruiz A, Frutos MD, Guzman G, Ramos-Molina B, Cordoba-Chacon J. 2023. Hepatocyte PPARγ contributes to the progression of non-alcoholic steatohepatitis in male and female obese mice. Cell Mol Life Sci. doi: 10.1007/s00018-022-04629-z | PMID: 36629912
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Coppola I, Brouwers B, Walker L, Alar C, Meulemans S, White A, Ramos-Molina B (CA), Creemers JWM. 2022. Loss of hypothalamic Furin affects POMC to proACTH cleavage and feeding behavior in high-fat diet-fed mice. Mol Metab. doi: 10.1016/j.molmet.2022.101627 | PMID: 36374777
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Núñez-Sánchez MA, Herisson FM, et al., Caplice NM, Gahan CGM. 2022. Microbial bile salt hydrolase activity influences gene expression profiles and gastrointestinal maturation in infant mice. Gut Microbes. doi: 10.1080/19490976.2022.2149023 | PMID: 36420990
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Kuchay MS, Martínez-Montoro JI, Llamoza-Torres CJ, Fernández-García JC, Ramos-Molina B (CA). 2022. Liver cirrhosis and sarcopenia: a dreadful combination. Hepatobiliary Surg Nutr. doi: 10.21037/hbsn-22-355 | PMID: 36268240
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Fernández-García JC, Barrios-Rodríguez R, Asenjo-Plaza M, Ramos-Molina B, et al., Martínez-González MÁ, Jiménez-Moleón JJ, Tinahones FJ. 2022. Metformin, testosterone, or both in men with obesity and low testosterone: A double-blind, parallel-group, randomized controlled trial. Metabolism. doi: 10.1016/j.metabol.2022.155290 | PMID: 35985506
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Kuchay MS, Martínez-Montoro JI, Kaur P, Fernández-García JC, Ramos-Molina B (CA). 2022. Non-alcoholic fatty liver disease-related fibrosis and sarcopenia: An altered liver-muscle crosstalk leading to increased mortality risk. Ageing Res Rev. doi: 10.1016/j.arr.2022.10169 | PMID: 35843589
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Martínez-Montoro JI, Kuchay MS, et al., Fernández-García JC, Ramos-Molina B (CA). 2021. Gut Microbiota and Related Metabolites in the Pathogenesis of Non-Alcoholic Steatohepatitis and its Resolution after Bariatric Surgery. Obesity Reviews. doi: 10.1111/obr.13367 | PMID: 34729904
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Brouwers B, Coppola I, Vints K, et al., Ramos-Molina B (CA), Creemers JW. 2021. Loss of Furin in β cells induces an mTORC1-ATF4 anabolic pathway that leads to β cell dysfunction. Diabetes. 2020 Dec 4:db200474. doi: 10.2337/db20-0474 | PMID: 33277337
CA: Corresponding Author.
CFA: Co-First Author.
CLA: Co-Last Author.



